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Yet alongside these marvels, we have weathered unprecedented challenges: a global pandemic that redefined healthcare delivery and vaccine technology, conflicts that have tested international resolve, and economic turbulence that has strained the fabric of global cooperation.\nThese convergent dynamics — technological breakthroughs and societal transformations — demand more than reactive governance and status-quo. They require an anticipation of future science, followed by action.\nThat is why the GESDA Science Breakthrough Radar® has never been more essential. This fifth edition represents something unique: the collective visions of the future of 2,500 scientists spanning 40 areas of research, mapping year after year the evolution of the scientific landscape across 5, 10, and 25-year horizons. This is not mere speculation — it is rigorous anticipation rooted in a solid methodology designed to equip decision-makers, legislators, diplomats, thought leaders and the broader public with the strategic intelligence needed to navigate an uncertain future accelerated by advances in science and technology.\nCombining Anticipation and Action: Use the Future to Build the Present\nGESDA combines anticipation and action. While others debate the implications of emerging science, we build the infrastructure for harnessing tomorrow's breakthroughs. The Open Quantum Institute, established in partnership with CERN, UBS, and over 20 nations, exemplifies this approach. Rather than waiting for quantum technologies to mature, we are actively shaping their development to serve humanity's greatest challenges, from climate modelling to drug discovery, in line with the UN Sustainable Development Goals.\nThis year's GESDA Science Breakthrough Radar highlights nine transformative domains that will define the next quarter-century: artificial intelligence that transcends current limitations, cognitive enhancement that expands human potential, engineering of human biology that could halt or reverse ageing and grow transplantable organs, ecological science that could restore life on our planet, pathogen biology that prepares us for future pandemics, the geopolitics of science and technology that makes us understand the increased importance of science in international relations, our accelerating understanding of language and its evolution, mathematical breakthroughs that will unlock solutions we cannot yet imagine and, as a fresh and more transversal contribution, how these anticipated science and technology breakthroughs will challenge our fundamental assumptions about human existence and social conditions at a planetary level — a phenomenon that we summarise in the newly-coined term Planetarised Humanity.\nLeadership in Transition\nAs GESDA enters its sixth year, we celebrate both continuity and renewal. Sandro Giuliani's pioneering leadership as CEO established GESDA as a unique force in anticipatory science diplomacy. Now, under the dynamic steering of Professor Marilyne Andersen as Director General — whose distinguished career at EPFL and exceptional leadership experience uniquely qualify her for this moment — GESDA is positioned to expand its influence and impact. We are pleased that Sandro Giuliani will continue to support us as Senior Advisor to the Board.\nOur global footprint has expanded dramatically, promoting International Geneva around the world through events and activities. Nearly half a million visitors experienced and interacted with our Geneva Public Portal to Anticipation at the 2025 World Expo in Osaka — an immersive journey into possible futures shaped by scientific breakthroughs, developed in collaboration with Professor Sarah Kenderdine’s laboratory at EPFL.\nOur anticipatory leadership programmes, which are supported by the Wellcome Trust, are cultivating a new generation of decision-makers equipped to anticipate and act on the challenges ahead. Building on the fourth Science Diplomacy Week in Geneva in May this year, GESDA adapted the programme to new audiences and contexts in Singapore, Manila and San José, with additional activities planned in Istanbul and Pretoria.\nThe NeuroFutures Imperative\nPerhaps no initiative better exemplifies GESDA's unique approach to anticipatory science diplomacy than NeuroFutures, launched at this year's Geneva Science and Diplomacy Anticipation Summit. This global alliance of philanthropic foundations and partners represents a crucial intervention at a pivotal moment. Brain-computer interfaces are advancing at exponential speed, promising to restore function to those with paralysis, enhance human cognition, and fundamentally alter the boundary between mind and machine.\nThe decisions made in the next few years will determine whether these technologies amplify human flourishing or fuel new social inequalities. NeuroFutures embodies GESDA's core philosophy: rather than waiting to regulate technologies after they emerge, we are creating the frameworks for responsible development in real-time, ensuring that transformative capabilities serve all of humanity.\nThe Anticipation Urgency\nThe scientific breakthroughs detailed in this report are not distant possibilities — they are emerging realities. These developments will reshape geopolitics, economics, social structures, and the very meaning of human identity. The nations, institutions, and leaders who understand and anticipate these changes will thrive. Those who do not will be left behind.\nWe invite you to engage with the GESDA Science Breakthrough Radar not as passive observers, but as active participants in shaping the future. The future is not something that happens to us — it is something we create through the choices we make today.\nThe science is clear. The opportunities are unprecedented. The time for action is now.\nPeter Brabeck-Letmathe, Chairman of the Board of Directors of the Geneva Science and Diplomacy Anticipator\n\nPatrick Aebischer, Vice Chairman of the Board of Directors of the Geneva Science and Diplomacy Anticipator\n\nGeneva - Switzerland - October 2025\n","text":"The world has been reshaped by forces that seemed like science fiction just half a decade ago. Artificial intelligence has evolved from laboratory curiosity to civilisational catalyst. Brain-machine interfaces are turning thought into action, liberating those trapped by paralysis. The exploitation of space has accelerated beyond governmental monopolies into a new frontier of human possibility. Yet alongside these marvels, we have weathered unprecedented challenges: a global pandemic that redefined healthcare delivery and vaccine technology, conflicts that have tested international resolve, and economic turbulence that has strained the fabric of global cooperation.\n\nThese convergent dynamics — technological breakthroughs and societal transformations — demand more than reactive governance and status-quo. They require an anticipation of future science, followed by action.\n\nThat is why the GESDA Science Breakthrough Radar® has never been more essential. This fifth edition represents something unique: the collective visions of the future of 2,500 scientists spanning 40 areas of research, mapping year after year the evolution of the scientific landscape across 5, 10, and 25-year horizons. This is not mere speculation — it is rigorous anticipation rooted in a solid methodology designed to equip decision-makers, legislators, diplomats, thought leaders and the broader public with the strategic intelligence needed to navigate an uncertain future accelerated by advances in science and technology.\n\n**Combining Anticipation and Action: Use the Future to Build the Present**\n\nGESDA combines anticipation and action. While others debate the implications of emerging science, we build the infrastructure for harnessing tomorrow's breakthroughs. The Open Quantum Institute, established in partnership with CERN, UBS, and over 20 nations, exemplifies this approach. Rather than waiting for quantum technologies to mature, we are actively shaping their development to serve humanity's greatest challenges, from climate modelling to drug discovery, in line with the UN Sustainable Development Goals.\n\nThis year's GESDA Science Breakthrough Radar highlights nine transformative domains that will define the next quarter-century: artificial intelligence that transcends current limitations, cognitive enhancement that expands human potential, engineering of human biology that could halt or reverse ageing and grow transplantable organs, ecological science that could restore life on our planet, pathogen biology that prepares us for future pandemics, the geopolitics of science and technology that makes us understand the increased importance of science in international relations, our accelerating understanding of language and its evolution, mathematical breakthroughs that will unlock solutions we cannot yet imagine and, as a fresh and more transversal contribution, how these anticipated science and technology breakthroughs will challenge our fundamental assumptions about human existence and social conditions at a planetary level — a phenomenon that we summarise in the newly-coined term Planetarised Humanity.\n\n**Leadership in Transition**\n\nAs GESDA enters its sixth year, we celebrate both continuity and renewal. Sandro Giuliani's pioneering leadership as CEO established GESDA as a unique force in anticipatory science diplomacy. Now, under the dynamic steering of Professor Marilyne Andersen as Director General — whose distinguished career at EPFL and exceptional leadership experience uniquely qualify her for this moment — GESDA is positioned to expand its influence and impact. We are pleased that Sandro Giuliani will continue to support us as Senior Advisor to the Board.\n\nOur global footprint has expanded dramatically, promoting International Geneva around the world through events and activities. Nearly half a million visitors experienced and interacted with our Geneva Public Portal to Anticipation at the 2025 World Expo in Osaka — an immersive journey into possible futures shaped by scientific breakthroughs, developed in collaboration with Professor Sarah Kenderdine’s laboratory at EPFL.\n\nOur anticipatory leadership programmes, which are supported by the Wellcome Trust, are cultivating a new generation of decision-makers equipped to anticipate and act on the challenges ahead. Building on the fourth Science Diplomacy Week in Geneva in May this year, GESDA adapted the programme to new audiences and contexts in Singapore, Manila and San José, with additional activities planned in Istanbul and Pretoria.\n\n**The NeuroFutures Imperative**\n\nPerhaps no initiative better exemplifies GESDA's unique approach to anticipatory science diplomacy than NeuroFutures, launched at this year's Geneva Science and Diplomacy Anticipation Summit. This global alliance of philanthropic foundations and partners represents a crucial intervention at a pivotal moment. Brain-computer interfaces are advancing at exponential speed, promising to restore function to those with paralysis, enhance human cognition, and fundamentally alter the boundary between mind and machine.\n\nThe decisions made in the next few years will determine whether these technologies amplify human flourishing or fuel new social inequalities. NeuroFutures embodies GESDA's core philosophy: rather than waiting to regulate technologies after they emerge, we are creating the frameworks for responsible development in real-time, ensuring that transformative capabilities serve all of humanity.\n\n**The Anticipation Urgency**\n\nThe scientific breakthroughs detailed in this report are not distant possibilities — they are emerging realities. These developments will reshape geopolitics, economics, social structures, and the very meaning of human identity. The nations, institutions, and leaders who understand and anticipate these changes will thrive. Those who do not will be left behind.\n\nWe invite you to engage with the GESDA Science Breakthrough Radar not as passive observers, but as active participants in shaping the future. The future is not something that happens to us — it is something we create through the choices we make today.\n\nThe science is clear. The opportunities are unprecedented. The time for action is now.\n\n*Peter Brabeck-Letmathe, Chairman of the Board of Directors of the Geneva Science and Diplomacy Anticipator*\n<ImageAsset slug=\"peter-brabeck-letmathe-signature\" id=\"65c55cee9e947c438698aa21\" />\n\n*Patrick Aebischer, Vice Chairman of the Board of Directors of the Geneva Science and Diplomacy Anticipator*\n<ImageAsset slug=\"patrick-aebischer-signature\" id=\"65c55cee9e947c438698aa1f\" />\n\n*Geneva - Switzerland - October 2025*"},"openGraph":{"title":null,"description":{"plain":"We stand at an extraordinary inflection point in human history. 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When GESDA was founded five years ago by the Swiss government with the support from the Canton and City of Geneva, and private sector partners, we anticipated change accelerated by science and technology — but even we could not have foreseen the breathtaking velocity of transformation that would follow."},"outro":{"id":"6a8f4888824a4b3e882d6efc_outro","text":""},"videos":[],"imageAssets":[],"organisations":[],"people":[],"embeds":{"citations":[],"pages":[],"people":[],"imageAssets":[{"id":"65c55cee9e947c438698aa1f","slug":"patrick-aebischer-signature","image":{"id":"image_gesda-22/image-asset/patrick-aebischer-signature_image__signature-Aebischer1","url":"https://res.cloudinary.com/shapeable/image/upload/v1668986576/gesda-22/image-asset/patrick-aebischer-signature_image__signature-Aebischer1.jpg","url2x":null,"width":672,"height":364,"type":"image/jpeg"}},{"id":"65c55cee9e947c438698aa21","slug":"peter-brabeck-letmathe-signature","image":{"id":"image_gesda-22/image-asset/peter-brabeck-letmathe-signature_image__signature-brabeck","url":"https://res.cloudinary.com/shapeable/image/upload/v1668986578/gesda-22/image-asset/peter-brabeck-letmathe-signature_image__signature-brabeck.jpg","url2x":null,"width":240,"height":162,"type":"image/jpeg"}}]},"banners":[{"id":"66e916d88bd10096b1c5145c","name":"Letter from the chairmen","slug":"letter-from-the-chairmen","title":null,"description":{"id":"66e916d88bd10096b1c5145c_description","text":""},"alternateText":null,"image":{"id":"image_gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr","url":"https://res.cloudinary.com/shapeable/image/upload/v1760338889/gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr.webp","url2x":null,"width":3958,"height":2167,"type":"image/webp","thumbnails":{"halfBanner":{"url":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_780/v1760338889/gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr.webp","url2x":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_1560/v1760338889/gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr.webp"},"mainBanner":{"url":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_1440/v1760338889/gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr.webp","url2x":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_2880/v1760338889/gesda-platform/banner/letter-from-the-chairmen_image__Letter_from_the_chairmen_2026_bn1hvr.webp"}}}}],"authors":[{"id":"65c55d249e947c438698b1f7","name":"Peter Brabeck-Letmathe","slug":"peter-brabeck-letmathe","path":"/people/peter-brabeck-letmathe","position":"Chairman of the Board of Directors","__typename":"Platform_Person","bio":{"id":"65c55d249e947c438698b1f7_bio","html":"<p>Born in Austria in 1944, Mr Brabeck-Letmathe graduated from the University of World Trade in Vienna with a degree in economics. After joining Nestlé Group in 1968, he spent a significant part of his career in Latin America before being transferred to Nestlé’s international headquarters in Vevey as Senior Vice President. Appointed Executive Vice President as of 1992 and Member of the Executive Board, he was in charge of strategic business units, sales &amp; marketing and corporate communications. He led Nestlé Group from 1997 to 2008, first as CEO until 2005 and then as Chairman &amp; CEO. In April 2008, he stepped down as CEO and remained Chairman of Nestlé S.A. On 6 April 2017, Mr Brabeck-Letmathe was appointed Chairman Emeritus of Nestlé S.A. Mr Brabeck-Letmathe also serves as Vice Chairman of the Foundation Board of the World Economic Forum and as Chairman of the Foundation Board of the Verbier Festival. He is Chairman of the Supervisory Board of Biologique Recherche and Chairman of the Advisory Board of SES-imagotag. He is the former Chairman and now an independent board member of Formula One Group and serves as a member of the Board of Directors of Salt Mobile SA. He is also Chairman of the Business Policy International Advisory Board of San Telmo Business School. Before that, he served on the boards of Roche, Credit Suisse, L’Oréal and Exxon Mobil Corporation. In addition, he was Chairman of the 2030 Water Resources Group, a public-private partnership that operates within the World Bank.</p>\n"},"openGraph":{"image":{"thumbnails":{"bubble":{"url":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_64/v1668987513/gesda-22/person/peter-brabeck-letmathe_photo__peter-brabeck-letmathe_3_lls9w8.jpg","url2x":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_128/v1668987513/gesda-22/person/peter-brabeck-letmathe_photo__peter-brabeck-letmathe_3_lls9w8.jpg"},"card":{"url":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_480/v1668987513/gesda-22/person/peter-brabeck-letmathe_photo__peter-brabeck-letmathe_3_lls9w8.jpg","url2x":"https://res.cloudinary.com/shapeable/image/upload/c_limit,w_960/v1668987513/gesda-22/person/peter-brabeck-letmathe_photo__peter-brabeck-letmathe_3_lls9w8.jpg"}}}}},{"id":"65c55d249e947c438698b1f2","name":"Patrick Aebischer","slug":"patrick-aebischer","path":"/people/patrick-aebischer","position":"Vice-Chairman of the Board of Directors","__typename":"Platform_Person","bio":{"id":"65c55d249e947c438698b1f2_bio","html":"<p>Professor Aebischer is President Emeritus of the Swiss Federal Institute of Technology in Lausanne (EPFL).</p>\n<p>During his 16-year term as EPFL President, from 2000 to 2016, he transformed the school and established it as a world-calibre university of science and technology. He is also a member of the Brain Mind Institute at EPFL’s School of Life Sciences. Prof Aebischer obtained degrees in medicine (1980) and neuroscience (1983) from the Universities of Geneva and Fribourg. From 1984 to 1992, he was a professor at Brown University’s Department of Neuroscience and Department of Biomaterials, Artificial Organs and Cellular Technology in the US. He returned to Switzerland in autumn 1992 as a full professor at the University of Lausanne and Director of the Division of Surgical Research and the Gene Therapy Centre at the Lausanne University Hospital (CHUV). Prof Aebischer is a member of the Singapore Health and Biomedical Sciences International Advisory Council (HBMS IAC), of the Scientific Committee of the Italian Institute of Technology (IIT) and of the International Advisory Board of Sabanci University in Istanbul. He also chairs the Advisory Committee of École Polytechnique in Paris. He serves on the boards of several not-for-profit organizations including the Swiss Polar Foundation, the Montreux Jazz Festival and the Verbier Festival. Prof Aebischer is a member of the Boards of Directors of Nestlé and Logitech. He is a former Vice Chairman of the Board of Directors of Lonza. He is Chairman of the Novartis Venture Fund (NVF) and a Senior Partner at +ND Capital, a venture capital firm that invests in disruptive technology in the life, physical and data sciences. 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tank.\n"},"image":{"url":"https://res.cloudinary.com/shapeable/image/upload/v1760413449/gesda-platform/site/gesda-radar-website_thumbnail__Screenshot_2025-10-14_at_11.42.59_o2cgxm.png","type":"image/png","thumbnails":{"full":{"url":"https://res.cloudinary.com/shapeable/image/upload/v1760413449/gesda-platform/site/gesda-radar-website_thumbnail__Screenshot_2025-10-14_at_11.42.59_o2cgxm.png"}}}},"termsAndConditions":{"text":""},"privacyPolicy":{"text":"At the Geneva Science and Diplomacy Anticipator (hereafter referred to as ‘GESDA’), we respect your privacy. We want to ensure that you get the information, content, and experiences that matter most to you. GESDA is committed to protecting the privacy of its stakeholders, communities, and other contacts.\n\n## Scope\n\nThis privacy policy applies to all personal data processed by full-time and part-time employees, volunteers when acting on behalf of GESDA, contractors and partners doing business on behalf of GESDA, as well as all legal entities, all operating locations in all countries, and all business processes conducted by GESDA.\n\n## Information Collected\n\n#### What information do we collect?\n\nGESDA collects the following personal data in line with the use purposes explained in a subsequent section:\n\n  * Your name and contact details\n  * Online profile data/usage\n  * Contact information\n  * Social media profile information\n  * Education and professional information\n  * Registration and participation in GESDA events and activities - Information about service usage\n  * Cookies\n  * Authentication data\n  * Location information\n  * Author and peer review information\n  * Other information you upload or provide to us\n\n#### How do we use your information?\n\nGESDA uses (and, where specified, shares) your personal information for the following purposes:\n\n  * To provide support or other services. GESDA may use your personal information to provide you with support or other services that you have ordered or requested. GESDA may also use your personal information to respond directly to your requests for information, including registrations for webinars, or other specific requests, or pass your contact information to the appropriate GESDA supplier or reseller for further follow-up related to your interests.\n  * To provide information based on your needs and respond to your requests. GESDA may use your personal information to provide you with notices of new product releases and service developments.\n  * To administer products. GESDA may contact you if you make use of (digital) products we offer, to confirm certain information (for example, that you did not experience problems in a download process). We may also use this information to confirm compliance with licensing and other terms of use and may share it with your company/institution.\n  * To assist in your participation in GESDA activities. GESDA will communicate with you, if you are participating in certain GESDA activities such as the GESDA Summit, authoring or reviewing a GESDA article, or GESDA humanitarian activities. GESDA may send you information such as update messages related to those activities (such as but not limited to the event's content, and event logistics)\n  * To update you on relevant GESDA events and opportunities. GESDA may communicate with you regarding relevant GESDA events and opportunities.\n  * To protect GESDA content and services. We may use your information to prevent potentially illegal activities and to enforce our terms and conditions.\n  * To get feedback or input from you. In order to deliver products and services of most interest to our stakeholders, from time to time, we may ask you to provide us input and feedback (for example through surveys).\n\n#### How can you control your information?\n\nYou can control the information we have about you and how we use as follows:\n\n  * If you are a registered guest for the GESDA Annual Summit 2021, any request for review, revise or correction of your personal data can be sent to summit@global.gesda specifying your request.\n\n#### Personal data about minors and children\n\nGESDA does not knowingly collect data from or about children under 16 without the permission of parent(s)/guardian(s). If we learn that we have collected personal information from a child under 16, we will delete that information as quickly as possible. If you believe that we might have any information from or about a child under age 16, please contact us.\n\n#### How will you know if the Privacy Policy is changed?\n\nGESDA may update its Privacy Policy from time to time. If we make any material changes you will be notified by means of a notice on our website prior on the date the change becomes effective. We encourage you to periodically review this page for the latest information on our privacy practices.\n\n## Technical And Regulatory Information\n\n#### Logging practices\n\nGESDA automatically records the Internet Protocol (IP) addresses of visitors. The IP address is a unique number assigned to every computer on the internet. Generally, an IP address changes each time you connect to the internet (it is a \"dynamic\" address). Note, however, that if you have a broadband connection, depending on your individual circumstance, the IP address that we collect may contain information that could be deemed identifiable. This is because, with some broadband connections, your IP address doesn't change (it is \"static\") and could be associated with your personal computer.\n\nAs well as recording the IP addresses of users, GESDA may also keep track of sites that users visited immediately prior to visiting GESDA's website and the search terms they used to find it. We keep track of the pages visited on GESDA's website, the amount of time spent on those pages and the types of searches done on them. Your searches remain confidential and anonymous. GESDA uses this information only for statistical purposes to find out which pages users find most useful and to improve the website.\nGESDA also captures and stores information that you transmit. This may include:\n\n  * Browser/Device type/version\n  * Operating system used\n  * Media Access Control (MAC) address\n  * Date and time of the server request\n  * Volume of data transferred\n\n#### External links behaviour\n\nSome of the links on GESDA's websites link to other sites created and maintained by other public- and/or private-sector organizations. GESDA provides these links solely for your information and convenience. When you transfer to an outside website, you are leaving the GESDA domain, and GESDA's information management policies no longer apply. GESDA encourages you to read the privacy statement of each external website that you visit before you provide any personal data.\n\n#### Cookies and web beacons\n\nCookies and web beacons are electronic placeholders that are placed on your device by websites to track your individual movements on that website over time. GESDA uses both session-based cookies (which last only for the duration of the user's session) and persistent cookies (which remain on your device and provide information about the session you are in and waits for the next time you use that site again).\n\nThese cookies and web beacons provide useful information to GESDA, enabling us to recognize repeat users, facilitate the user's access to and use of our sites, allows us to track usage behavior, and to balance the usage of our websites on all GESDA web servers.\nTracking cookies, third-party cookies, and other technologies such as web beacons may be used to process additional information, enable non-core functionalities on the GESDA website and enable third-party functions (such as a social media \"share\" link). We may also include web beacons and other similar technology in promotional email messages to determine whether the messages have been opened.\n\n#### Do Not Track (DNT)\n\nThe online advertising industry has self-regulatory initiatives designed to provide consumers a choice in the types of ads they may see online and to conveniently opt-out from online behavioral ads served by some or all of the companies participating in these programs. Our websites do not respond to DNT consumer browser settings.\n\n#### Responses to legal requests\n\nGESDA reserves the right to share your information to respond to duly authorized information requests of governmental authorities or where required by law.\n\n#### Your data rights\n\nGESDA complies with all applicable data privacy laws and regulations including, but not limited to, the General Data Protection Regulation (GDPR) and the California Consumer Privacy Act (CCPA). Under these laws and regulations, you may have certain rights to your data. 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